Image: Actinoplanes sp.
NovoBiotic Pharmaceuticals is a privately held, early stage biotechnology company focused on the discovery and development of new drugs from natural sources.
The Gap in New Drug Discovery
We focus on the discovery of new antibiotics targeting serious drug-resistant infections. While many marketed antibiotics are derived from microbes found in the soil, few new classes have been introduced since the 1960s. Large pharmaceutical companies have exhaustively screened the readily culturable microbes, which represent <1% of microbes in the environment. Thus, the vast majority of microbes in nature have remained uncultured and inaccessible to drug discovery. Our discovery platform overcomes this long-standing problem by providing access to the >99% of microbes previously believed to be “unculturable”, allowing us to explore a virtually unlimited diversity of natural products.